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Scream (also informally known as Scream 5) is a 2022 American slasher film directed by Matt Bettinelli-Olpin and Tyler Gillett and written by James Vanderbilt and Guy Busick. It is the fifth installment in the Scream film series. Though billed as a relaunch of the film series, the film is a direct sequel to Scream 4 (2011), and the first in the series not to be directed by Wes Craven, who died in 2015. It stars franchise newcomers Melissa Barrera, Mason Gooding, Jenna Ortega, and Jack Quaid, with Marley Shelton, Courteney Cox, David Arquette, Neve Campbell, and Roger L. Jackson reprising their roles from previous installments.

Filming took place in Wilmington, North Carolina, from September to November 2020. The film is scheduled to be released in the United States on January 14, 2022, by Paramount Pictures.